sub:assertion {
d:DB00541 dv:ddi-interactor-in dr:DB00541_DB00951 .
d:DB00951 dv:ddi-interactor-in dr:DB00541_DB00951 .
dr:DB00541_DB00951 dct:identifier "drugbank_resource:DB00541_DB00951" ;
dct:title "DDI between Vincristine and Isoniazid - Isoniazid, a strong CYP3A4 inhibitor, may increase the serum concentration of Vincristine by decreasing its metabolism. Consider alternate therapy to avoid Vincristine toxicity. Monitor for changes in the therapeutic and adverse effects of Vincristine if Isoniazid is initiated, discontinued or dose changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Vincristine and Isoniazid - Isoniazid, a strong CYP3A4 inhibitor, may increase the serum concentration of Vincristine by decreasing its metabolism. Consider alternate therapy to avoid Vincristine toxicity. Monitor for changes in the therapeutic and adverse effects of Vincristine if Isoniazid is initiated, discontinued or dose changed. [drugbank_resource:DB00541_DB00951]"@en .
}