@prefix this: <https://w3id.org/kpxl/ios/ds/np/RAGRTZAgCvGWT3ZpznWZ_DOOXsu2AXnIwDrHq7F99eL_g> .
@prefix sub: <https://w3id.org/kpxl/ios/ds/np/RAGRTZAgCvGWT3ZpznWZ_DOOXsu2AXnIwDrHq7F99eL_g#> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix nt: <https://w3id.org/np/o/ntemplate/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix orcid: <https://orcid.org/> .
@prefix ns1: <http://purl.org/np/> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix npx: <http://purl.org/nanopub/x/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix sp: <https://w3id.org/linkflows/superpattern/terms/> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:spi a sp:SuperPatternInstance;
    rdfs:label "the protein TDP-43 generally contributes to the transcription of STMN2 in human motor neurons";
    sp:hasContextClass <http://www.wikidata.org/entity/Q101404862>;
    sp:hasObjectClass <http://purl.org/np/RAiUYY1dbEDbcsscapEmbMMHsgJmjEJ1yUoNsxZIH1r90#transcription-of-stmn2>;
    sp:hasQualifier sp:canGenerallyQualifier;
    sp:hasRelation sp:contributesTo;
    sp:hasSubjectClass <http://www.wikidata.org/entity/Q21133247> .
}

sub:provenance {
  sub:activity a sp:FormalizationActivity;
    prov:used <https://doi.org/10.1038/s41593-018-0300-4>, sub:quote;
    prov:wasAssociatedWith orcid:0000-0003-1099-3328 .
  
  sub:assertion prov:wasGeneratedBy sub:activity .
  
  sub:quote prov:value "expression of STMN2, which encodes a microtubule regulator, declined after TDP-43 knockdown and TDP-43 mislocalization as well as in patient-specific motor neurons";
    prov:wasQuotedFrom <https://doi.org/10.1038/s41593-018-0300-4> .
}

sub:pubinfo {
  <http://www.wikidata.org/entity/Q101404862> nt:hasLabelFromApi "human motor neuron - cell type of Homo sapiens" .
  
  <http://www.wikidata.org/entity/Q21133247> nt:hasLabelFromApi "TAR DNA binding protein - mammalian protein found in Homo sapiens" .
  
  orcid:0000-0002-1267-0234 foaf:name "Tobias Kuhn" .
  
  sub:author-list rdf:_1 orcid:0000-0003-1099-3328 .
  
  sub:sig npx:hasAlgorithm "RSA";
    npx:hasPublicKey "MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQD4Wj537OijfOWVtsHMznuXKISqBhtGDQZfdO6pbb4hg9EHMcUFGTLbWaPrP783PHv8HMAAPjvEkHLaOHMIknqhaIa5236lfBO3r+ljVdYBElBcLvROmwG+ZGtmPNZf7lMhI15xf5TfoaSa84AFRd5J2EXekK6PhaFQhRm1IpSYtwIDAQAB";
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    npx:hasSignatureTarget this:;
    npx:signedBy orcid:0000-0002-1267-0234 .
  
  this: dct:created "2025-04-09T05:29:46.325Z"^^xsd:dateTime;
    dct:creator orcid:0000-0002-1267-0234;
    dct:isPartOf <https://doi.org/10.3233/DS-210039>;
    dct:license <https://creativecommons.org/licenses/by/4.0/>;
    npx:hasNanopubType <https://w3id.org/kpxl/ios/ds/terms/DataScienceNanopub>;
    npx:introduces sub:spi;
    npx:wasCreatedAt <https://nanodash.knowledgepixels.com/>;
    <http://purl.org/ontology/bibo/authorList> sub:author-list;
    prov:wasDerivedFrom ns1:RAmG2bXxwkIzARk4Mda-lqZU0RVnkpX7hUHBIPcdLHQUU;
    <https://w3id.org/linkflows/reviews/isUpdateOf> ns1:RA5rRFy9eDTZSTyVeuTrAO7aCg_JPcq1cVmWWjc-kjFOM;
    nt:wasCreatedFromProvenanceTemplate ns1:RAE1wniOy0yO39PlK9QkQ-wqbC3q-R2nXraP5huu8W39k;
    nt:wasCreatedFromPubinfoTemplate ns1:RAOGu9Lh0BD4tbIRB9RG6RGRA_ObDh75NTbIqaWgxxs8M,
      <https://w3id.org/np/RA0J4vUn_dekg-U1kK3AOEt02p9mT2WO03uGxLDec1jLw>, <https://w3id.org/np/RA16U9Wo30ObhrK1NzH7EsmVRiRtvEuEA_Dfc-u8WkUCA>,
      <https://w3id.org/np/RA5R_qv3VsZIrDKd8Mr37x3HoKCsKkwN5tJVqgQsKhjTE>, <https://w3id.org/np/RARW4MsFkHuwjycNElvEVtuMjpf4yWDL10-0C5l2MqqRQ>,
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    nt:wasCreatedFromTemplate ns1:RAy3tITXPlULFLXxAxek39GLqLdqKkNM5hIzUOZxxjMmI .
}