http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#head http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#provenance http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://rdf.disgenet.org/resource/gda/DGN6fd1b29b529e60d0605a6676e90389d1 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/7124 http://rdf.disgenet.org/resource/gda/DGN6fd1b29b529e60d0605a6676e90389d1 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C2936349 http://rdf.disgenet.org/resource/gda/DGN6fd1b29b529e60d0605a6676e90389d1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001123 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#provenance http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://purl.org/dc/terms/description [In contrast, at 17 months of age, APP;C3(-/-) mice showed significant changes of up to twofold increased total Abeta and fibrillar amyloid plaque burden in midfrontal cortex and hippocampus, which correlated with (1) significantly increased Tris-buffered saline (TBS)-insoluble Abeta(42) levels and reduced TBS-soluble Abeta(42) and Abeta(40) levels in brain homogenates, (2) a trend for increased Abeta levels in the plasma, (3) a significant loss of neuronal-specific nuclear protein-positive neurons in the hippocampus, and (4) differential activation of microglia toward a more alternative phenotype (e.g., significantly increased CD45-positive microglia, increased brain levels of interleukins 4 and 10, and reduced levels of CD68, F4/80, inducible nitric oxide synthase, and tumor necrosis factor).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/18562603 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/dc/terms/created 2017-10-17T13:16:47+02:00 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1033991.RAGG0nKaBYuUVT-QjU1dRk4WTizpqv6cKpEvPmBNbG6Ps http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0