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[The present study establishes a novel permissive mouse immunocompetent orthotopic colon carcinoma model focusing on non-replicating Adv-TKs, a well-established adjuvant treatment in cancer and comparing its antitumor efficacy and safety profile with those of the two newly synthesized oncolytic Ad vectors, M7 and M8, formed by the insertion of a fragment of HSV-TK cDNA into the deleted 6.7 K/gp19 K or ADP in the E3 region to the E1A CR2-deleted Ad5 vectors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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