@prefix this: <
http://bio2rdf.org/drugbank:DB01189_nanopub.RAFkuV2gyiKfZ8FaByi8VgKzZvRliwWT8vaiw22e9kSxA
> .
@prefix sub: <
http://bio2rdf.org/drugbank:DB01189_nanopub.RAFkuV2gyiKfZ8FaByi8VgKzZvRliwWT8vaiw22e9kSxA#
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix orcid: <
http://orcid.org/
> .
@prefix codebase: <
https://github.com/tkuhn/bio2rdf2nanopub
> .
@prefix version: <
https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349
> .
@prefix instance: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB
> .
@prefix process: <
https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix v: <
http://bio2rdf.org/bio2rdf_vocabulary:
> .
@prefix d: <
http://bio2rdf.org/drugbank:
> .
@prefix dv: <
http://bio2rdf.org/drugbank_vocabulary:
> .
@prefix dr: <
http://bio2rdf.org/drugbank_resource:
> .
@prefix dcat: <
http://www.w3.org/ns/dcat#
> .
@prefix npx: <
http://purl.org/nanopub/x/
> .
sub:head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:publicationInfo
;
a
np:Nanopublication
.
}
sub:assertion
{
d:DB01189
v:identifier
"DB01189" ;
v:namespace
"drugbank" ;
v:uri
"http://bio2rdf.org/drugbank:DB01189" ;
v:x-identifiers.org
<
http://identifiers.org/drugbank/DB01189
> ;
dv:drugbank-id
"APRD00907" , "DB01189" ;
dv:x-ahfs
<
http://bio2rdf.org/ahfs:28:04.00
> ;
dv:x-atc
<
http://bio2rdf.org/atc:N01AB07
> ;
dv:x-cas
<
http://bio2rdf.org/cas:57041-67-5
> ;
dv:x-chebi
<
http://bio2rdf.org/chebi:4445
> ;
dv:x-chemspider
<
http://bio2rdf.org/chemspider:38403
> ;
dv:x-dpd
<
http://bio2rdf.org/dpd:2227428
> ;
dv:x-kegg
<
http://bio2rdf.org/kegg:C07519
> , <
http://bio2rdf.org/kegg:D00546
> ;
dv:x-ndc
<
http://bio2rdf.org/ndc:10019-641-24
> ;
dv:x-pharmgkb
<
http://bio2rdf.org/pharmgkb:PA164749136
> ;
dv:x-pubchemcompound
<
http://bio2rdf.org/pubchem.compound:42113
> ;
dv:x-pubchemsubstance
<
http://bio2rdf.org/pubchem.substance:46505270
> ;
dv:x-wikipedia
<
http://bio2rdf.org/wikipedia:Desflurane
> ;
dct:description
"Desflurane is a highly fluorinated methyl ethyl ether used for maintenance of general anaesthesia. Volatile agents such as desflurane may activate GABA channels and hyperpolarize cell membranes. In addition, they may inhibit certain calcium channels and therefore prevent release of neurotransmitters and inhibit glutamate channels. Volatile anesthetics easily partition into cellular membranes and could expand the volume of the cell membrane and subsequently distort channels necessary for sodium ion flux and the development of action potentials necessary for synaptic transmission. Desflurane preconditions human myocardium against ischemia through activation of mitochondrial K(ATP) channels, adenosine A1 receptor, and alpha and beta adrenoceptors."@en ;
dct:identifier
"drugbank:DB01189" ;
dct:title
"Desflurane"@en ;
a
dv:Drug
;
rdfs:label
"Desflurane [drugbank:DB01189]"@en ;
rdfs:seeAlso
<
http://www.drugbank.ca/drugs/DB01189
> , <
http://www.drugs.com/cons/desflurane-inhalation-oral-nebulization.html
> , <
http://www.rxlist.com/cgi/generic2/desflurane.htm
> .
}
sub:provenance
{
sub:assertion
prov:wasDerivedFrom
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
dr:bio2rdf.dataset.drugbank.R3
dcat:distribution
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
> .
<
http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz
>
dct:created
"2015-01-09T17:00:50-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00
>
pav:retrievedOn
"2014-11-12T07:57:03-05:00"^^
xsd:dateTime
;
prov:wasDerivedFrom
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
> .
<
http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip
>
prov:wasAttributedTo
<
http://drugbank.ca
> .
}
sub:publicationInfo
{
sub:signature.MCwCFFUCsWXPjkMA
npx:hasPublicKey
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npx:hasSignature
"MCwCFFUCsWXPjkMAiZ2/VjbrUAq7PxwXAhR7CpDDAMzPJHIAeZ5EM44KsAhOOA==" ;
npx:signedBy
instance:
.
this:
dct:created
"2018-03-30T11:10:48.910+02:00"^^
xsd:dateTime
;
dct:license
<
https://creativecommons.org/licenses/by-nc/4.0/
> ;
npx:hasSignatureElement
sub:signature.MCwCFFUCsWXPjkMA
;
prov:wasGeneratedBy
process:
.
instance:
prov:specializationOf
codebase:
;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
process:
dct:identifier
"7720f136-841b-4851-a6e4-ad20a409a475" ;
prov:used
version:
;
prov:wasAssociatedWith
instance:
;
prov:wasStartedBy
orcid:0000-0002-1267-0234
.
version:
dct:isVersionOf
codebase:
;
pav:version
"eda7951a5f6c622c5d2132f50c3093138484a349" ;
prov:wasAttributedTo
orcid:0000-0002-1267-0234
.
}