sub:assertion {
d:DB00440 dv:ddi-interactor-in dr:DB00440_DB01124 .
d:DB01124 dv:ddi-interactor-in dr:DB00440_DB01124 .
dr:DB00440_DB01124 dct:identifier "drugbank_resource:DB00440_DB01124" ;
dct:title "DDI between Trimethoprim and Tolbutamide - The strong CYP2C9 inhibitor, Tolbutamide, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Tolbutamide is initiated, discontinued or dose changed."@en ;
a dv:Drug-Drug-Interaction ;
rdfs:label "DDI between Trimethoprim and Tolbutamide - The strong CYP2C9 inhibitor, Tolbutamide, may decrease the metabolism and clearance of Trimethoprim, a CYP2C9 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimethoprim if Tolbutamide is initiated, discontinued or dose changed. [drugbank_resource:DB00440_DB01124]"@en .
}