. . . . . . . . . . . . . . . . "bp(GOBP:\"response to endoplasmic reticulum stress\") -> bp(MESHPP:Apoptosis)" . "p(HGNC:HSPA5) -| (bp(GOBP:\"response to endoplasmic reticulum stress\") -> bp(MESHPP:Apoptosis))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "The induction of CHOP by LPS was delayed and weak, in comparison with CHOP induction by ER stress-inducer thapsigargin. In addition, LPS-pre-treatment or overexpression of ER chaperone, IgH chain binding protein (BiP), prevented ER stress-mediated apoptosis. LPS plus IFN-gamma-treated macrophages produce a larger amount of nitric oxide (NO) in comparison with LPS-treated cells. Treatment with the NO donor, SNAP (S-nitro-N-acetyl-dl-penicillamine), induces CHOP at an earlier period than LPS treatment. The depletion of NO retards CHOP induction and prevents apoptosis in LPS plus IFN-gamma-treated cells." . . "Selventa" . . . . "2014-07-03T14:33:37.526+02:00"^^ . . .