sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_7 ;
pav:version "20131211" .
sub:_6 prov:value "Fig 3. HIF-1? counteracts Myc activity. (A) Effect of ?ODD on Myc transcriptional activity was examined with an hTERT luciferase reporter in HCT116 cells. .....Unlike wild-type HIF-1?, ?ODD constitutively activated HIF-1-mediated reporter gene in transient transfection (Figure 2A). We then inactivated ?ODD transcriptional activity via simultaneous mutations (L795V, C800S, L818S, and L822V) that disrupt p300/CBP binding (Gu et al, 2001; Dames et al, 2002; Freedman et al, 2002). As expected, this ?ODD LCLL mutant was unable to activate the HIF-1 reporter (Figure 2A)." ;
prov:wasQuotedFrom pubmed:15071503 .
sub:_7 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:15071503 ;
prov:wasDerivedFrom beldoc: ,
sub:_6 .
}