@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_head { this: np:hasAssertion dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_assertion; np:hasProvenance dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_provenance; np:hasPublicationInfo dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_publicationInfo; a np:Nanopublication . dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_assertion a np:Assertion . dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_provenance a np:Provenance . dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_publicationInfo a np:PublicationInfo . } dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_assertion { miriam-gene:1786 a ncit:C16612 . lld:C0006142 a ncit:C7057 . dgn-gda:DGN0d66a489746613bc10061219e0cfb672 sio:SIO_000628 miriam-gene:1786, lld:C0006142; a sio:SIO_001121 . } dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_provenance { dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_assertion dcterms:description "[These observations combine to strongly suggest that: (a) a subset of breast cancer cell lines express a hypermethylator phenotype, (b) the hypermethylation defect in these breast cancer cell lines is related to aberrant overexpression of DNMT activity, (c) overexpression of DNMT3b protein significantly contributes to the elevated DNMT activity observed in tumor cells expressing this phenotype, and (d) the six-gene hypermethylator signature characterized in breast cancer cell lines defines a distinct cluster of primary basal-like breast cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:18221536; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP651808.RAF4nnv4IvDhuBgD3TBijZE8f1XZyO3vhT2p2awIGiaDs130_publicationInfo { this: dcterms:created "2016-05-13T12:46:40+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }