. . . . . . . . . . . . . . . "kin(complex(SCOMP:\"p85/p110 PI3Kinase Complex\")) -> r(HGNC:MCAM)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "In this study, we show that there is a reciprocal regulation loop between AKT and MelCAM. Pharmacological inhibition of AKT in human melanoma cell lines substantially reduced the expression of MelCAM. Overexpression of constitutively active AKT upregulated the levels of MelCAM in melanoma cell lines, whereas expression of a dominant-negative PI-3 kinase downregulated MelCAM." . . "Selventa" . . . . "2014-07-03T14:32:09.958+02:00"^^ . . .