@prefix this: <http://bio2rdf.org/drugbank:DB00421_nanopub.RAEiDXu2GOjCQaVHchAOeTSiMLJzyOK1g0TIftHzpu96E> .
@prefix sub: <http://bio2rdf.org/drugbank:DB00421_nanopub.RAEiDXu2GOjCQaVHchAOeTSiMLJzyOK1g0TIftHzpu96E#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix pav: <http://purl.org/pav/> .
@prefix orcid: <http://orcid.org/> .
@prefix codebase: <https://github.com/tkuhn/bio2rdf2nanopub> .
@prefix version: <https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> .
@prefix instance: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> .
@prefix process: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix v: <http://bio2rdf.org/bio2rdf_vocabulary:> .
@prefix d: <http://bio2rdf.org/drugbank:> .
@prefix dv: <http://bio2rdf.org/drugbank_vocabulary:> .
@prefix dr: <http://bio2rdf.org/drugbank_resource:> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:publicationInfo ;
    a np:Nanopublication .
}
sub:assertion {
   d:DB00421 v:identifier "DB00421" ;
    v:namespace "drugbank" ;
    v:uri "http://bio2rdf.org/drugbank:DB00421" ;
    v:x-identifiers.org <http://identifiers.org/drugbank/DB00421> ;
    dv:drugbank-id "APRD01234" , "DB00421" ;
    dv:x-ahfs <http://bio2rdf.org/ahfs:24:32.20> ;
    dv:x-atc <http://bio2rdf.org/atc:C03DA01> ;
    dv:x-bindingdb <http://bio2rdf.org/bindingdb:50228080> ;
    dv:x-cas <http://bio2rdf.org/cas:52-01-7> ;
    dv:x-chebi <http://bio2rdf.org/chebi:9241> ;
    dv:x-chemspider <http://bio2rdf.org/chemspider:5628> ;
    dv:x-dpd <http://bio2rdf.org/dpd:613223> ;
    dv:x-gtp <http://bio2rdf.org/gtp:2875> ;
    dv:x-iuphar <http://bio2rdf.org/iuphar:2875> ;
    dv:x-kegg <http://bio2rdf.org/kegg:C07310> , <http://bio2rdf.org/kegg:D00443> ;
    dv:x-ndc <http://bio2rdf.org/ndc:0781-1599-01> ;
    dv:x-pdb <http://bio2rdf.org/pdb:SNL> ;
    dv:x-pharmgkb <http://bio2rdf.org/pharmgkb:PA451483> ;
    dv:x-pubchemcompound <http://bio2rdf.org/pubchem.compound:5833> ;
    dv:x-pubchemsubstance <http://bio2rdf.org/pubchem.substance:46508525> ;
    dv:x-wikipedia <http://bio2rdf.org/wikipedia:Spironolactone> ;
    dct:description "A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)"@en ;
    dct:identifier "drugbank:DB00421" ;
    dct:title "Spironolactone"@en ;
    a dv:Drug ;
    rdfs:label "Spironolactone [drugbank:DB00421]"@en ;
    rdfs:seeAlso <http://www.drugbank.ca/drugs/DB00421> , <http://www.drugs.com/spironolactone.html> , <http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/ald1010.shtml> , <http://www.rxlist.com/cgi/generic/spiron.htm> .
}
sub:provenance {
   sub:assertion prov:wasDerivedFrom <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  dr:bio2rdf.dataset.drugbank.R3 dcat:distribution <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime ;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> .
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime ;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> .
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> prov:wasAttributedTo <http://drugbank.ca> .
}
sub:publicationInfo {
   sub:signature.MCwCFCmpgHSI1I5- npx:hasPublicKey "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" ;
    npx:hasSignature "MCwCFCmpgHSI1I5+Kk+dNDrYE5UxLimJAhQDJC/chWdYfah16/HEiQrfKfAWyw==" ;
    npx:signedBy instance: .
  this: dct:created "2018-03-30T11:10:52.905+02:00"^^xsd:dateTime ;
    dct:license <https://creativecommons.org/licenses/by-nc/4.0/> ;
    npx:hasSignatureElement sub:signature.MCwCFCmpgHSI1I5- ;
    prov:wasGeneratedBy process: .
  instance: prov:specializationOf codebase: ;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
  process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475" ;
    prov:used version: ;
    prov:wasAssociatedWith instance: ;
    prov:wasStartedBy orcid:0000-0002-1267-0234 .
  version: dct:isVersionOf codebase: ;
    pav:version "eda7951a5f6c622c5d2132f50c3093138484a349" ;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}