http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#Head http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#assertion http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#provenance http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#assertion http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_2 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0003824 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=11180 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/UBERON_0002107 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/Superoxides http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_1 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#assertion http://www.w3.org/2000/01/rdf-schema#label cat(p(HGNC:SOD2)) -| a(SCHEM:Superoxides) http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_4 http://www.w3.org/ns/prov#value However, at several upstream sites of the MRC (most probably complexes I and III), a small fraction of these electrons can directly react with oxygen, to generate the superoxide anion radical. This radical is then dismutated by the mitochondrial manganese superoxide dismutase (MnSOD) into hydrogen peroxide (H2O2), which is detoxified into water by the mitochondrial glutathione peroxidase. Hence, in the normal (non-diseased) state, most of the ROS generated by the MRC is detoxified by the mitochondrial antioxidant defences. http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18705745 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18705745 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#_4 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc#pubinfo http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://purl.org/dc/terms/created 2014-07-03T14:33:23.921+02:00 http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAEMOgQIxRYhQUrHERE231KThbEDept_6QJjSFLU_pSgc http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234