sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "1.4" .
  sub:_5 prov:value "80 nM wortmannin reduced both ET-1 and EGF-induced Erk 2 activation. Quantitative densitometric analysis indicated that wortmannin caused a 32% reduction in the phosphorylated:unphosphorylated Erk 2 ratio in ET-1-stimulated cells. ET-1-induced Erk 2 phosphorylation was only partially blocked in the presence of both inhibitors. The degree of inhibition (36%) was similar to that caused by tryphostin AG1478 or wortmannin alone. These results indicate that the tryphostin AG1478-insensitive activation of Erk2 is only partially attributable to the contribution of a PI3K-dependent pathway." ;
    prov:wasQuotedFrom pubmed:11016663 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:11016663 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}