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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#_3 http://www.w3.org/ns/prov#value Here we show that p27(Kip1) progressively accumulates in the nucleus of pancreatic beta cells in mice that lack either insulin receptor substrate 2 (Irs2(-/-)) or the long form of the leptin receptor (Lepr(-/-) or db/db). Deletion of the gene encoding p27(Kip1) (Cdkn1b) ameliorated hyperglycemia http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15685168 http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15685168 http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#_3 http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY#pubinfo http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY http://purl.org/dc/terms/created 2014-07-03T14:30:31.323+02:00 http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAE-sFOxRgtVZN9rIaCReiRMKqtQHjbNYuR2ypxD-i7pY http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234