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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#_3 http://www.w3.org/ns/prov#value To better understand the consequences of mtDNA deletions, we microarrayed six cell types containing mtDNA deletions from KSS and CPEO patients. Indicated are transcripts shared and downregulated in cells harboring mtDNA deletions in >3 experiments (Table 4); Differentially expressed genes were identified by comparing GeneChips designated as baseline (muscles, myoblasts, fibroblasts, and lymphoblasts from healthy subjects, fusion control cell lines, and parental 143B cells) with the ones that represent the experimental parameters (muscles, myoblasts, fibroblasts, and lymphoblasts from patients, mutant cybrids, and 143B rho zero cells) using a difference in mean fluorescence ? 30 and a P value < 0.05; 37 downregulated genes; 26 upregulated genes; http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17157191 http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17157191 http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#_3 http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU#pubinfo http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU http://purl.org/dc/terms/created 2014-07-03T14:30:48.577+02:00 http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RADzYIG2g84bMC-umj1hLFvDOfoWsmCXSvfpIdTQd-gbU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234