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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#_3 http://www.w3.org/ns/prov#value For this purpose, A549 cells were incubated in various sequences of normoxic and hypoxic (1% O2) intervals (Fig. 1A) as follows: normoxia (N), hypoxia for 2 h (H2), hypoxia for 2 h followed by reoxygenation for 2 h (H2R), intermittent hypoxia for twice 2 h interrupted by 2 h of normoxia (IH4), IH4 followed by 2 h of reoxygenation (IH4R), intermittent hypoxia for three times 2 h interrupted twice by 2 h of normoxia (IH6), and continuous hypoxia for 6 h (H6). HIF-1A was most strongly induced in H6 and IH6....Expression of both Nrf2 and Trx1 was upregulated in IH4R and IH6.....Expression of the NADPH oxidase subunit NOX1 was enhanced in IH4, IH4R, and IH6 compared to N. http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/20347035 http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/20347035 http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#_3 http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#pubinfo http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo http://purl.org/dc/terms/created 2014-07-03T14:30:55.250+02:00 http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234