@prefix this: <http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RADxQIupYEQVSXVshXTNAs--g2EjPHReBewPHVoiiNuuo#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 geneProductOf: hgnc:4910 ;
    a Protein: .
  sub:_2 occursIn: atcc:CCL-185.aspx , species:9606 ;
    rdf:object sub:_1 ;
    rdf:predicate belv:increases ;
    rdf:subject go:0001666 ;
    a rdf:Statement .
  sub:assertion rdfs:label "bp(GO:\"response to hypoxia\") -> p(HGNC:HIF1A)" .
}
sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_4 ;
    pav:version "1.4" .
  sub:_3 prov:value "For this purpose, A549 cells were incubated in various sequences of normoxic and hypoxic (1% O2) intervals (Fig. 1A) as follows: normoxia (N), hypoxia for 2 h (H2), hypoxia for 2 h followed by reoxygenation for 2 h (H2R), intermittent hypoxia for twice 2 h interrupted by 2 h of normoxia (IH4), IH4 followed by 2 h of reoxygenation (IH4R), intermittent hypoxia for three times 2 h interrupted twice by 2 h of normoxia (IH6), and continuous hypoxia for 6 h (H6). HIF-1A was most strongly induced in H6 and IH6....Expression of both Nrf2 and Trx1 was upregulated in IH4R and IH6.....Expression of the NADPH oxidase subunit NOX1 was enhanced in IH4, IH4R, and IH6 compared to N." ;
    prov:wasQuotedFrom pubmed:20347035 .
  sub:_4 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:20347035 ;
    prov:wasDerivedFrom beldoc: , sub:_3 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:30:55.250+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}