http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_head http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_provenance http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://identifiers.org/ncbigene/3383 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0684249 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN9d5e0eea1c5e7aa50fd911c18267972d http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/3383 http://rdf.disgenet.org/resource/gda/DGN9d5e0eea1c5e7aa50fd911c18267972d http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0684249 http://rdf.disgenet.org/resource/gda/DGN9d5e0eea1c5e7aa50fd911c18267972d http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_provenance http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://purl.org/dc/terms/description [This concept is based on the following findings: (a) engagement of beta1 integrins on certain lung cancer cells by a specific antibody or by ligand matrices such as fibronectin and collagen markedly reduced ICAM-1 expression on the cell surface and induced sICAM-1; (b) down-regulation of ICAM-1 by stimulation of beta1 integrins was abrogated by tyrosine kinase inhibitors or by transfection of dominant negative truncations of focal adhesion kinase (FAK); (c) engagement of beta1 integrins also reduced ICAM-1-dependent adhesion of lung cancer cells to T cells, a process completely inhibited by tyrosine kinase inhibitors and by transfection of dominant negative forms of FAK; and (d) stimulation of beta1 integrins prevented killing of lung cancer cells by autologous CTLs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/11280762 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://purl.org/pav/importedOn 2015-02-27 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/dc/terms/created 2015-08-25T14:42:19+02:00 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v3.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP473953.RADwXm2uYbVDUrBVAPMVh4RnOzDSj4vG12bAaPm7qFidQ http://purl.org/pav/version v3.0.0.0 http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v3.0.0