. . . . . . . . . . . . . . . . . . . . . . . "p(HGNC:ARRB1) -> (p(HGNC:IGF1) -> kin(p(HGNC:MAPK3)))" . "p(HGNC:IGF1) -> kin(p(HGNC:MAPK3))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "from full text - In BE cells transfected with b-arrestin1 siRNA no pERK signals were detected (Fig. 1, C and D). These data provide further evidence that b-arrestin1 is necessary for IGF-1-induced ERK activation. We also investigated whether b-arrestin2 played a similar role. However, no significant reduction in IGF-1-stimulated pERK was observed in BE cells transfected with b-arrestin2 siRNA (Fig. 1, C and D). In contrast, down-regulation of b-arrestin2 levels led to an increase in both basal and IGF-1-stimulated ERK activity that was sustained up to 60 min (Fig. 1, C and D)." . . "Selventa" . . . . "2014-07-03T14:33:08.521+02:00"^^ . . .