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m(HGNC:MIRLET7B) -| r(HGNC:LOXL4)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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Combining microarray techniques with DNA sequence analysis to identify potential let-7 targets, we discovered 838 genes with a let-7 binding site in their 3'UTR, that were down-regulated upon overexpression of let-7b. (From Suppl Table 1). To identify potential let-7 targets, we looked for genes consistently down-regulated in the presence of let-7 (i.e., genes within cluster 2 or 4) that also contain at least one let-7 recognition site within their 3’ UTR, resulting in 838 genes (Supplementary Table 1).
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