sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_6 ; pav:version "1.4" . sub:_5prov:value "The human interstitial collagenase (MMP-1) promoter has been also shown to be a Ras-responsive promoter by virtue of the presence of ETS and AP-1 cis-elements, which act synergistically to activate Ras-dependent transcription of the gene (15, 16). Similarly to what was observed previously with the synthetic ORE reporter, ESE-3 was able to repress the -1200 to +63 collagenase promoter response to Ras (Fig. 6B). In both cases, expression of ETS-2 resulted in enhanced expression of the reporter in these cells" ; prov:wasQuotedFrompubmed:11259407 . sub:_6rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:11259407 ; prov:wasDerivedFrombeldoc: , sub:_5 . }