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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#_5 http://www.w3.org/ns/prov#value Treatment of MIF (10 microg/ml) led to phosphorylation of multiple cellular proteins of 60, 34 and 30 kDa in comparison with the control and the phosphorylated 60 kDa protein was considered to be an autophosphorylated member of the Src tyrosine kinases and autophosphorylation was enhanced at 3 minutes after stimulation but the protein level was sustained up to 1 hour. Further, treatment of PP2, a selective inhibitor of Src kinases markedly suppressed the upregulation of MMP13 induced by MIF. Thus, MIF enhanced the kinase activity but protein level was not increased. http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11755189 http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11755189 http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#_5 http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY#pubinfo http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY http://purl.org/dc/terms/created 2014-07-03T14:29:59.900+02:00 http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RADiBVJR9bp7SZfCZjssD8FLR5m1Wf-F0t3BQMlK_NCxY http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234