[ { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY", "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ], "http://www.nanopub.org/nschema#hasAssertion" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#pubinfo" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#Head" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_1", "@type" : [ "http://amigo.geneontology.org/amigo/term/GO:0003824" ], "http://semanticscience.org/resource/SIO_000139" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_2" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_2", "@type" : [ "http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080" ], "http://purl.obolibrary.org/obo/RO_0002204" : [ { "@id" : "http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=11916" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_3", "@type" : [ "http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement" ], "http://purl.obolibrary.org/obo/BFO_0000066" : [ { "@id" : "http://purl.obolibrary.org/obo/CL_0000746" }, { "@id" : "http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#object" : [ { "@id" : "http://purl.bioontology.org/ontology/MSH/D017209" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate" : [ { "@id" : "http://www.selventa.com/vocabulary/increases" } ], "http://www.w3.org/1999/02/22-rdf-syntax-ns#subject" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_1" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#assertion", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "cat(p(HGNC:TNFRSF1A)) -> bp(MESHPP:Apoptosis)" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#assertion" }, { "@graph" : [ { "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel", "http://purl.org/dc/elements/1.1/description" : [ { "@value" : "Approximately 61,000 statements." } ], "http://purl.org/dc/elements/1.1/rights" : [ { "@value" : "Copyright (c) 2011-2012, Selventa. All rights reserved." } ], "http://purl.org/dc/elements/1.1/title" : [ { "@value" : "BEL Framework Large Corpus Document" } ], "http://purl.org/pav/authoredBy" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_5" } ], "http://purl.org/pav/version" : [ { "@value" : "20131211" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_4", "http://www.w3.org/ns/prov#value" : [ { "@value" : "GSK-3b activity restrains pro-apoptotic signaling from death receptors (ie, TNF-R1 {Official Gene Symbol: TNFRSF1A}, Fas, DR4 {Official Gene Symbol: TNFRSF10A}, DR5 {Official Gene Symbol: TNFRSF10B}).77?80 Inhibition of GSK-3b in the cells with activated death receptors enhanced activation of caspases-8 and -3, Bid cleavage and apoptosis, indicating that GSK-3b suppresses pro-apoptotic signals upstream of caspase activation.78?80 Thus, inactivation of GSK-3b under the condition of stimulation of death receptors promotes apoptosis." } ], "http://www.w3.org/ns/prov#wasQuotedFrom" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/19506320" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_5", "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@value" : "Selventa" } ] }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#assertion", "http://www.w3.org/ns/prov#hadPrimarySource" : [ { "@id" : "http://www.ncbi.nlm.nih.gov/pubmed/19506320" } ], "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel" }, { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#_4" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#provenance" }, { "@graph" : [ { "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2014-07-03T14:33:34.810+02:00" } ], "http://purl.org/pav/createdBy" : [ { "@id" : "http://orcid.org/0000-0001-6818-334X" }, { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] } ], "@id" : "http://www.tkuhn.ch/bel2nanopub/RADcCdsib8V_6Alv68erbIEEPgcbu0g8oiqS7bB7cf4mY#pubinfo" } ]