sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_5 ;
pav:version "20131211" .
sub:_4 prov:value "GSK-3b activity restrains pro-apoptotic signaling from death receptors (ie, TNF-R1 {Official Gene Symbol: TNFRSF1A}, Fas, DR4 {Official Gene Symbol: TNFRSF10A}, DR5 {Official Gene Symbol: TNFRSF10B}).77?80 Inhibition of GSK-3b in the cells with activated death receptors enhanced activation of caspases-8 and -3, Bid cleavage and apoptosis, indicating that GSK-3b suppresses pro-apoptotic signals upstream of caspase activation.78?80 Thus, inactivation of GSK-3b under the condition of stimulation of death receptors promotes apoptosis." ;
prov:wasQuotedFrom pubmed:19506320 .
sub:_5 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:19506320 ;
prov:wasDerivedFrom beldoc: ,
sub:_4 .
}