. . . . . . . . . . . . . "cat(p(HGNC:EDNRB)) -| a(SCHEM:\"cyclic AMP\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "EDNRB reduces cyclic AMP (cAMP) production via Gai, thus leading to protein kinase A (PKA) inhibition. Since chemical PKA blockade mimics the effects exerted by ET-3 on ENS progenitors, it is likely that the RET-EDNRB interaction is mediated by PKA (fig. 1) [19]. This is supported by the finding that serine 686 in the juxtamembrane domain of RET is phosphorylated by PKA, thereby enhancing RET-mediated lamellipodia formation [20]." . . "Selventa" . . . . "2014-07-03T14:32:35.825+02:00"^^ . . .