http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#Head http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#assertion http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#provenance http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#pubinfo http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#assertion http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_2 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_3 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:101833 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:102853 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_4 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_5 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_5 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:101833 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_6 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_4 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/directlyIncreases http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_1 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#assertion http://www.w3.org/2000/01/rdf-schema#label complex(p(MGI:Elk1),p(MGI:Elk4)) => tscript(p(MGI:Elk1)) http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_8 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_7 http://www.w3.org/ns/prov#value . This region contains three juxtaposed SRE (serum response element)/Ets site pairs known to be important for egr-1 activity in response to exogenous stimuli. Site-specific mutations of individual SRE and Ets sites within this region each reduced GH inducibility of the promoter. Use of these site-specific mutations in EMSA showed that disruption of either Ets or SRE sites abrogated ternary complex formation at the composite sites. DNA binding of ternary complexes, but not binary complexes, in EMSA was rapidly and transiently increased by GH. EMSA supershifts indicated these ternary complexes contained serum response factor (SRF) and the Ets factors Elk-1 and Sap-1a. Coexpression of Sap-1a and Elk-1 resulted in a marked increase in GH induction of egr-1 promoter activity, although transfection with expression vectors for either Ets factor alone did not significantly enhance the GH response. http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10194767 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10194767 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#_7 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI#pubinfo http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://purl.org/dc/terms/created 2014-07-03T14:31:29.966+02:00 http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RADYB_dngVdi9jRzHsM21Y8mCODtCvUvTfJHVXBcXJ-WI http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234