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Alvimopan is contraindicated for use if patients have been dosed with opioids for more than 7 consecutive days. http://bio2rdf.org/drugbank_resource:DB01551_DB06274 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://bio2rdf.org/drugbank_vocabulary:Drug-Drug-Interaction http://bio2rdf.org/drugbank_resource:DB01551_DB06274 http://www.w3.org/2000/01/rdf-schema#label DDI between Dihydrocodeine and Alvimopan - Opioids may enhance Alvimopan toxicity, especially when opiate use for more than 7 days is in place prior to alvimopan initiation. Alvimopan is contraindicated for use if patients have been dosed with opioids for more than 7 consecutive days. 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