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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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GILZ {Official Gene Symbol: Tsc22d3} has been proposed as a DEX-induced protein able to bind and inhibit p65NF-{kappa}B activity (Di Marco et al., 2007Go). We evaluated, by real-time PCR, the effect of DEX treatment in WT and PPAR-{alpha}KO cells on GILZ expression. Results in Fig. 6a indicate that DEX induced an increase of GILZ mRNA expression in WT but not in PPAR-{alpha}KO mice. Moreover, this difference was even enhanced in carrageenan-treated WT mice, thus indicating that PPAR-{alpha} contributes to DEX-induced GILZ expression.
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2014-07-03T14:30:52.204+02:00
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