@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_head {
  this: np:hasAssertion dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_assertion;
    np:hasProvenance dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_provenance;
    np:hasPublicationInfo dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_assertion a np:Assertion .
  
  dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_provenance a np:Provenance .
  
  dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_assertion {
  miriam-gene:7291 a ncit:C16612 .
  
  lld:C0678222 a ncit:C7057 .
  
  dgn-gda:DGNff4f4a9b0c094f8d40e8d32f87526c7c sio:SIO_000628 miriam-gene:7291, lld:C0678222;
    a sio:SIO_001121 .
}

dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_provenance {
  dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_assertion dcterms:description
      "[Metformin treatment dynamically regulated the CD44(pos)CD24(neg/low) breast cancer stem cell immunophenotype, transcriptionally reprogrammed cells through decreased expression of key drivers of the EMT machinery including the transcription factors ZEB1, TWIST1 and SNAI2 (Slug) and the pleiotrophic cytokines TGFβs, and lastly impeded the propensity of breast cancer stem cells to form multicellular `microtumors` in non-adherent and non-differentiating conditions (i.e., `mammospheres`).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:20890129;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP515960.RADCTD5q7ZYUTnw5TDQxf4E_yzJHpQRTFmY40w28VL4qk130_publicationInfo {
  this: dcterms:created "2014-10-02T12:37:07+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}