@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .
dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_head {
   this: np:hasAssertion dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_assertion ;
    np:hasProvenance dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_provenance ;
    np:hasPublicationInfo dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_publicationInfo ;
    a np:Nanopublication .
  dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_assertion a np:Assertion .
  dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_provenance a np:Provenance .
  dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_publicationInfo a np:PublicationInfo .
}
dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_assertion {
   miriam-gene:2353 a ncit:C16612 .
  lld:C0282548 a ncit:C7057 .
  dgn-gda:DGN810975256e0c85bdb99d4abd8814c0df sio:SIO_000628 miriam-gene:2353 , lld:C0282548 ;
    a sio:SIO_001121 .
}
dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_provenance {
   dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_assertion dcterms:description "[We found that systemic inhibition of IGF-I signaling with a receptor-neutralizing antibody, or with inhibitors of PI-3 kinase (PI-3K), c-Jun kinase (JNK), or Akt, suppressed retinal Akt, JNK, HIF-1alpha, nuclear factor (NF)-kappaB, and AP-1 activity, vascular endothelial growth factor (VEGF) expression, as well as intercellular adhesion molecule-1 levels, leukostasis, and blood-retinal barrier breakdown, in a relevant animal model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_literature ;
    sio:SIO_000772 miriam-pubmed:15277220 ;
    prov:wasDerivedFrom dgn-void:befree-20140225 ;
    prov:wasGeneratedBy eco:ECO_0000203 .
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  dgn-void:source_evidence_literature a eco:ECO_0000212 ;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en ;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}
dgn-np:NP385576.RADBxByFdPcRifsqPj-CT30f528nTEoh-TVqprkyoew4k130_publicationInfo {
   this: dcterms:created "2014-10-02T12:35:49+02:00"^^xsd:dateTime ;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/> ;
    dcterms:rightsHolder dgn-void:IBIGroup ;
    dcterms:subject sio:SIO_000983 ;
    prv:usedData dgn-void:disgenetrdf ;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269> , <http://orcid.org/0000-0002-7534-7661> , <http://orcid.org/0000-0002-9383-528X> , <http://orcid.org/0000-0003-0169-8159> , <http://orcid.org/0000-0003-1244-7654> ;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159> ;
    pav:version "v2.1.0.0" .
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}