http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#Head http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#assertion http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#provenance http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#pubinfo http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#assertion http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=8031 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_2 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_1 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=4808 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#assertion http://www.w3.org/2000/01/rdf-schema#label complex(p(HGNC:HAND2),g(HGNC:NTRK1)) http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_3 http://www.w3.org/ns/prov#value Short interfering RNA knockdown of endogenous HAND2 and, to a lesser extent, HAND1 in neonatal sympathetic neurons cultured with NGF, reduced the expression of the NGF receptor tyrosine kinase TrkA (tropomyosin-related kinase A), as well as neuronal survival. Chromatin immunoprecipitation analysis showed that NGF promotes HAND2 binding to the TrkA minimal enhancer and that transfection of sympathetic neurons with a TrkA expression plasmid rescued the neurons from HAND knockdown. http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18724272 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18724272 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#_3 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4#pubinfo http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://purl.org/dc/terms/created 2014-07-03T14:30:53.448+02:00 http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RADBWq-AAIr6_ZZpt7j4a1Twkm2geWvHSRERD82j2vVj4 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234