@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_head { this: np:hasAssertion dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_assertion; np:hasProvenance dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_provenance; np:hasPublicationInfo dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_publicationInfo; a np:Nanopublication . dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_assertion a np:Assertion . dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_provenance a np:Provenance . dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_publicationInfo a np:PublicationInfo . } dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_assertion { miriam-gene:7076 a ncit:C16612 . lld:C0018802 a ncit:C7057 . dgn-gda:DGN0a6c39194cb1bb3bd5a2846eb75e4d3f sio:SIO_000628 miriam-gene:7076, lld:C0018802; a sio:SIO_001121 . } dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_provenance { dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_assertion dcterms:description "[The purpose of this review is fivefold: 1) to examine and redefine the myocardial matrix as a critical and dynamic entity with respect to the remodeling process encountered with MI, hypertension, or cardiomyopathic disease; 2) present the remarkable progress that has been made with respect to MMP/TIMP biology and how it relates to myocardial matrix remodeling; 3) to evaluate critical translational/clinical studies that have provided a cause-effect relationship between alterations in MMP/TIMP regulation and myocardial matrix remodeling; 4) to provide a critical review and analysis of current diagnostic, prognostic, and pharmacological approaches that utilized our basic understanding of MMP/TIMPs in the context of cardiac disease; and 5) most importantly, to dispel the historical belief that the myocardial matrix is a passive structure and supplant this belief that the regulation of matrix protease pathways such as the MMPs and TIMPs will likely yield a new avenue of diagnostic and therapeutic strategies for myocardial remodeling and the progression to heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:17928585; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP297324.RAD83-n_BnSbTxSEs3tGzTJFHQEz8-VuhGM0srvPOXzOU130_publicationInfo { this: dcterms:created "2014-10-02T12:34:49+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }