@prefix this: <http://bio2rdf.org/drugbank:DB01194_nanopub.RACwVUhQ88h99Vk7l64IFxH6APqBuQXwk5dqU7_icwwvs> .
@prefix sub: <http://bio2rdf.org/drugbank:DB01194_nanopub.RACwVUhQ88h99Vk7l64IFxH6APqBuQXwk5dqU7_icwwvs#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix pav: <http://purl.org/pav/> .
@prefix orcid: <http://orcid.org/> .
@prefix codebase: <https://github.com/tkuhn/bio2rdf2nanopub> .
@prefix version: <https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> .
@prefix instance: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> .
@prefix process: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix v: <http://bio2rdf.org/bio2rdf_vocabulary:> .
@prefix d: <http://bio2rdf.org/drugbank:> .
@prefix dv: <http://bio2rdf.org/drugbank_vocabulary:> .
@prefix dr: <http://bio2rdf.org/drugbank_resource:> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix npx: <http://purl.org/nanopub/x/> .
sub:head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:publicationInfo ;
    a np:Nanopublication .
}
sub:assertion {
  d:DB01194 v:identifier "DB01194" ;
    v:namespace "drugbank" ;
    v:uri "http://bio2rdf.org/drugbank:DB01194" ;
    v:x-identifiers.org <http://identifiers.org/drugbank/DB01194> ;
    dv:drugbank-id "APRD00475" , "DB01194" ;
    dv:x-ahfs <http://bio2rdf.org/ahfs:52:10.00> ;
    dv:x-atc <http://bio2rdf.org/atc:S01EC04> ;
    dv:x-bindingdb <http://bio2rdf.org/bindingdb:10885> ;
    dv:x-cas <http://bio2rdf.org/cas:138890-62-7> ;
    dv:x-chebi <http://bio2rdf.org/chebi:3176> ;
    dv:x-chemspider <http://bio2rdf.org/chemspider:62077> ;
    dv:x-dpd <http://bio2rdf.org/dpd:2238873> ;
    dv:x-kegg <http://bio2rdf.org/kegg:C07760> , <http://bio2rdf.org/kegg:D00652> ;
    dv:x-ndc <http://bio2rdf.org/ndc:0065-0275-25> ;
    dv:x-pdb <http://bio2rdf.org/pdb:BZU> ;
    dv:x-pharmgkb <http://bio2rdf.org/pharmgkb:PA164744929> ;
    dv:x-pubchemcompound <http://bio2rdf.org/pubchem.compound:68844> ;
    dv:x-pubchemsubstance <http://bio2rdf.org/pubchem.substance:46507071> ;
    dv:x-wikipedia <http://bio2rdf.org/wikipedia:Brinzolamide> ;
    dct:description "Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma."@en ;
    dct:identifier "drugbank:DB01194" ;
    dct:title "Brinzolamide"@en ;
    a dv:Drug ;
    rdfs:label "Brinzolamide [drugbank:DB01194]"@en ;
    rdfs:seeAlso <http://www.drugbank.ca/drugs/DB01194> , <http://www.drugs.com/cdi/brinzolamide-drops.html> , <http://www.rxlist.com/cgi/generic3/brinzolamide.htm> .
}
sub:provenance {
  sub:assertion prov:wasDerivedFrom <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  dr:bio2rdf.dataset.drugbank.R3 dcat:distribution <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime ;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> .
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime ;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> .
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> prov:wasAttributedTo <http://drugbank.ca> .
}
sub:publicationInfo {
  sub:signature.MCwCFD91sVniGiyA npx:hasPublicKey "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" ;
    npx:hasSignature "MCwCFD91sVniGiyAE5MZk0JUBCed/iUSAhQrOtXk8YBfesMLD5uhQLjYO4h5FA==" ;
    npx:signedBy instance: .
  this: dct:created "2018-03-30T11:10:51.725+02:00"^^xsd:dateTime ;
    dct:license <https://creativecommons.org/licenses/by-nc/4.0/> ;
    npx:hasSignatureElement sub:signature.MCwCFD91sVniGiyA ;
    prov:wasGeneratedBy process: .
  instance: prov:specializationOf codebase: ;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
  process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475" ;
    prov:used version: ;
    prov:wasAssociatedWith instance: ;
    prov:wasStartedBy orcid:0000-0002-1267-0234 .
  version: dct:isVersionOf codebase: ;
    pav:version "eda7951a5f6c622c5d2132f50c3093138484a349" ;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}