@prefix this: <http://www.tkuhn.ch/bel2nanopub/RACsJg45lTU1l0pQvjltoCUPgDc4LsGAlf_j8tmObSfTM> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RACsJg45lTU1l0pQvjltoCUPgDc4LsGAlf_j8tmObSfTM#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix nch: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-complexes/> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix hasPart: <http://purl.obolibrary.org/obo/BFO_0000051> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  nch:CK%20II%20Complex a ProteinComplex: .
  
  sub:_1 hasAgent: sub:_2;
    a go:0016301 .
  
  sub:_2 hasPart: nch:CK%20II%20Complex, sub:_3, sub:_4;
    a ProteinComplex: .
  
  sub:_3 geneProductOf: hgnc:11465;
    a Protein: .
  
  sub:_4 geneProductOf: hgnc:11327;
    a Protein: .
  
  sub:_5 occursIn: species:9606;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject go:0009411;
    a rdf:Statement .
  
  sub:assertion rdfs:label "bp(GO:\"response to UV\") -> kin(complex(complex(NCH:\"CK II Complex\"),p(HGNC:SUPT16H),p(HGNC:SSRP1)))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_7;
    pav:version "1.4" .
  
  sub:_6 prov:value "Here we describe identification and purification of a mammalian UV-activated protein kinase complex that phosphorylates Ser-392 of p53 in vitro. This kinase complex contains casein kinase 2 (CK2) and the chromatin transcriptional elongation factor FACT (a heterodimer of hSpt16 and SSRP1). In vitro studies show that FACT alters the specificity of CK2 in the complex such that it selectively phosphorylates p53 over other substrates including casein. In addition, phosphorylation by the kinase complex enhances p53 activity. These results thus provide a potential mechanism for p53 activation by UV irradiation.";
    prov:wasQuotedFrom pubmed:11239457 .
  
  sub:_7 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:11239457;
    prov:wasDerivedFrom beldoc:, sub:_6 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:29:54.514+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}