http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#Head http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#provenance http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#pubinfo http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_1 http://www.selventa.com/vocabulary/translocationFrom http://amigo.geneontology.org/amigo/term/GO:0005622 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_1 http://www.selventa.com/vocabulary/translocationOf http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_2 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_1 http://www.selventa.com/vocabulary/translocationTo http://amigo.geneontology.org/amigo/term/GO:0009986 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3430 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=3229 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_4 http://www.selventa.com/vocabulary/variantOf http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=10840 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00696 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_4 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_3 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_6 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CLO_0009251 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_6 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_5 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_1 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.w3.org/2000/01/rdf-schema#label p(HGNC:EGF) -> p(HGNC:SHC1,pmod(P,Y)) http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.w3.org/2000/01/rdf-schema#label surf(p(HGNC:ERBB2)) -> (p(HGNC:EGF) -> p(HGNC:SHC1,pmod(P,Y))) http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_8 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_7 http://www.w3.org/ns/prov#value An analysis using a phosphotyrosine-specific antibody revealed that in T47D/puro cells, two of the three Shc isoforms, p46shc and p52shc, became highly phosphorylated in response to EGF and NDF. In the T47D/5R cells, the NDFinduced tyrosine phosphorylation of both proteins was reduced by 90% (Fig. 7A). EGF-induced Shc phosphorylation was also reduced in these cells, albeit to a lesser extent (63 and 41% for p46shc and p52shc, respectively). http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/7532277 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/7532277 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#_7 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA#pubinfo http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://purl.org/dc/terms/created 2014-07-03T14:33:44.535+02:00 http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RACnoFHF37ObsXkM9saA5Ioq_eOkPS-6AypCMvgUrEHpA http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234