sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_4 ;
    pav:version "20131211" .
  sub:_3 prov:value "To monitor the ability of ATRA and VD to activate the genetic program underlying monocytic differentiation in the M2 cellular context, we have investigated the expression of VD-responsive genes (Fig. 8) such as HMSE-1, CD14, and hOC by RT-PCR and the expression of genes controlled by a functional VDRE, such as p21waf-1 (51) , or RARE, such as E3 (52) , IRF-1 (53) and p21waf-1 (68) , by Northern blot analysis after different times of ATRA or VD treatment. Fig. 8 shows that both ATRA and VD treatment of Kasumi-1 cells causes a rapid induction of HMSE-1, CD14, and hOC expression, demonstrating VDR involvement in ATRA-dependent monocytic differentiation of M2-type blast cells." ;
    prov:wasQuotedFrom pubmed:10446999 .
  sub:_4 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10446999 ;
    prov:wasDerivedFrom beldoc: , sub:_3 .
}