. . . . . . . . . . . . . "p(MGI:Il1b) -> p(MGI:Csf1)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "Osteoclast formation was higher in ovariectomized (OVX) mice than sham operated mice, ovariectomy also increased the mononuclear cell secretion of interleukin IL-1, tumor necrosis factor and M-CSF production. The production of M-CSF protein and mRNA via IL-1 was lowered by the treatment of estrogen or IL-1 receptor antagonist (IL-1ra bound to IL-1 receptors and competed with both IL-1 alpha and IL-1 beta without detectable IL-1 agonistic effects) in ovariectomized bone marrow cells." . . "Selventa" . . . . "2014-07-03T14:33:55.326+02:00"^^ . . .