[We systematically investigated the association of 48 SNPS in four vitamin D metabolizing genes CYP27A1, GC, CYP27B1 and CYP24A1 with serum 25-hydroxyvitamin D 25(OH)D and 1,25-dihydroxyvitamin D 1,25(OH)(2)D levels and the association of these SNPS and an additional 164 SNPS in eight downstream mediators of vitamin D signaling VDR, RXRA, RXRB, PPAR, NCOA1, NCOA2, NCOA3 and SMAD3 with prostate cancer risk in the 749 incident prostate cancer cases and 781 controls of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
Gene-disease associations inferred from text-mining the literature.
DisGeNET evidence - LITERATURE