@prefix this: <http://www.tkuhn.ch/bel2nanopub/RACCXUMbmceWLOR7GBiAUomNdLaJWFA52qM2QqIgM-ROY> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RACCXUMbmceWLOR7GBiAUomNdLaJWFA52qM2QqIgM-ROY#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix chebi: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix pfh: <http://resource.belframework.org/belframework/1.0/namespace/selventa-named-human-protein-families/> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix atcc: <http://www.lgcstandards-atcc.org/Products/All/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 hasAgent: sub:_2 ;
    a go:0016301 .
  sub:_2 geneProductOf: pfh:AKT%20Family ;
    a Protein: .
  sub:_3 occursIn: atcc:CCL-2.aspx , species:9606 ;
    rdf:object sub:_1 ;
    rdf:predicate belv:increases ;
    rdf:subject chebi:5586 ;
    a rdf:Statement .
  sub:assertion rdfs:label "a(CHEBI:\"hydrogen peroxide\") -> kin(p(PFH:\"AKT Family\"))" .
}
sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "ROS signals can amplify AKT signaling cascades in the forward direction through transient oxidative inactivation of the phosphatase and tensin homolog (PTEN) and other phosphatases that oppose AKT phosphorylation (21). Accordingly, we utilized the phosphorylation status of AKT as a central marker for signal transduction that can be modulated by H2O2. Accordingly, we utilized the phosphorylation status of AKT as a central marker for signal transduction that can be modulated by H2O2. Initial experiments tested the direct effects of H2O2 on AKT phosphorylation. Serum-starved control HeLa cells do not exhibit increases in pAKT/AKT ratios upon addition of H2O2  (Fig. 2D)." ;
    prov:wasQuotedFrom pubmed:20724658 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:20724658 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:30:55.342+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}