@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix chebi: . @prefix go: . @prefix scomp: . @prefix ProteinComplex: . @prefix hasAgent: . @prefix species: . @prefix occursIn: . @prefix obo: . @prefix do: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { scomp:Nfkb%20Complex a ProteinComplex: . sub:_1 hasAgent: scomp:Nfkb%20Complex; a go:0042789 . sub:_2 occursIn: do:1936, obo:CL_0000235, obo:UBERON_0001969, species:9606; rdf:object sub:_1; rdf:predicate belv:increases; rdf:subject chebi:41526; a rdf:Statement . sub:assertion rdfs:label "a(CHEBI:\"carbon monoxide\") -> tscript(complex(SCOMP:\"Nfkb Complex\"))" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "20131211" . sub:_3 prov:value "Interestingly, the HO effector molecules biliverdin/bilirubin and CO have also been implicated in the modulation of a range of signaling pathways, including the cGMP and MAPK system, by which they may modulate inflammatory processes and also be involved in ROS-mediated signaling (Adeagbo, 1997; Siow et al., 1999; Otterbein et al., 2000; Nath et al., 2001b). It is likely that HO effector molecules bilirubin and CO, similar to anti-oxidants and NO (De Caterina et al., 1995), play a role in the regulation of ROS-mediated pathways, since HO-1 knockout mice show increased nuclear staining of NF-B after exposure to hemoglobin, compared with control mice (Nath et al., 2001b)."; prov:wasQuotedFrom pubmed:12869663 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:12869663; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dct:created "2014-07-03T14:32:04.837+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }