sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_5 ; pav:version "1.4" . sub:_4prov:value "however, after stimulation with interleukin-1beta or tumor necrosis factor-alpha, levels of ESE-3 mRNA and protein increase dramatically by 24 h. ESE-3 mRNA and Protein Are Inducibly Expressed in Human Bronchial Smooth Muscle Cells after Treatment with TNF-{alpha} or IL-1beta To test the hypothesis that ESE-3 may be induced in other cells of the airways in response to inflammatory cytokines of relevance to asthma, we exposed HBSMC to TNF-{alpha} and IL-1beta. ESE-3 mRNA was induced 6 to 24 h after treatment with both cytokines, each at a concentration of 5 ng/ml, and detected by RT-PCR" ; prov:wasQuotedFrompubmed:12444029 . sub:_5rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:12444029 ; prov:wasDerivedFrombeldoc: , sub:_4 . }