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[(Clin Cancer Res., 8: 1904-1914, 2002) sheds light on all of these issues when they report on data that derive from a `triple threat` strategy, i.e., in vitro, in vivo, and ex vivo, to demonstrate that adenoviral infection of PTEN into PTEN-null PC3 prostate cancer cell lines results in decreased metastatic potential without significantly altering tumor size via the predominant mechanism of G(1) cell cycle arrest but not apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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