Nanopublications

sub:assertion {
  sub:_1 geneProductOf: rgd:3046 ;
    a RNA: .
  sub:_2 rdf:object sub:_1 ;
    rdf:predicate belv:increases ;
    rdf:subject chebi:5586 ;
    a rdf:Statement .
  sub:_3 occursIn: mesh:D005347 , mesh:D006321 , species:10116 ;
    rdf:object sub:_2 ;
    rdf:predicate belv:decreases ;
    rdf:subject chebi:50662 ;
    a rdf:Statement .
  sub:assertion rdfs:label "a(CHEBI:\"hydrogen peroxide\") -> r(RGD:Mapk3)" , "a(CHEBI:marimastat) -| (a(CHEBI:\"hydrogen peroxide\") -> r(RGD:Mapk3))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "1.4" .
  sub:_4 prov:value "GM 6001 (N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]- L-tryptophan methylamide), and BB 2516 ([2S-[N4(R(*)),2R(*),3S(*)]]-N4-[2,2-dimethyl-1- [(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2- methylpropyl) butanediamide, Marimastat), two MMP inhibitors, have been found to attenuate H2O2-induced c-JNK and ERK1/2 phosphorylation in rat heart fibroblasts (30)." ;
    prov:wasQuotedFrom pubmed:17406055 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:17406055 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}