@prefix this: <http://www.tkuhn.ch/bel2nanopub/RABvmQYWozDfoMSIP7_EJYCyyQfeeAFZCgj_Nho2GweUo> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RABvmQYWozDfoMSIP7_EJYCyyQfeeAFZCgj_Nho2GweUo#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix do: <http://disease-ontology.org/term/DOID:> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 geneProductOf: hgnc:12784 ;
    a Protein: .
  sub:_2 hasAgent: sub:_3 ;
    a go:0003824 .
  sub:_3 geneProductOf: hgnc:4043 ;
    a Protein: .
  sub:_4 occursIn: do:1909 , obo:CL_0000148 , species:9606 ;
    rdf:object sub:_2 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "p(HGNC:WNT5A) -> cat(p(HGNC:FZD5))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "20131211" .
  sub:_5 prov:value "Because Wnt5a binds to the receptor Frizzled-5, and by this interaction can exert its signaling effects (Ishikawa et al. 2001) and Sen et al. 2000 M. Sen, K. Lauterbach, H. El-Gabalawy, G.S. Firestein, M. Corr and D.A. Carson, Expression and function of wingless and frizzled homologs in rheumatoid arthritis, Proc. Natl. Acad. Sci. USA 97 (2000), pp. 2791?2796. View Record in Scopus | Cited By in Scopus (89)(Sen et al. 2000),.....Inhibition of the Fzd5 receptor results in a decrease in PKC activation. The Wnt5a transfectants were treated with a functional antibody to the receptor. This resulted in a decrease in PKC activation in the antibody-treated cells, but not the IgG-treated cells." ;
    prov:wasQuotedFrom pubmed:12086864 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:12086864 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:31:51.232+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}