@prefix this: <http://www.tkuhn.ch/bel2nanopub/RABn2yQ-bl4Wi1bMH3tZj4mmMX4gLLzTeoQIBJrYTALJ4> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RABn2yQ-bl4Wi1bMH3tZj4mmMX4gLLzTeoQIBJrYTALJ4#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix schem: <http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 geneProductOf: hgnc:12663 ;
    a Protein: .
  sub:_2 occursIn: obo:CLO_0009465 , species:9606 ;
    rdf:object sub:_1 ;
    rdf:predicate belv:increases ;
    rdf:subject schem:Oxidized%20Low%20Density%20Lipoprotein ;
    a rdf:Statement .
  sub:assertion rdfs:label "a(SCHEM:\"Oxidized Low Density Lipoprotein\") -> p(HGNC:VCAM1)" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_4 ;
    pav:version "20131211" .
  sub:_3 prov:value "Exposure of U937 cells to ox-LDL for 24 h resulted in a significant increase in HIF-1alpha, COX2, ICAM-1, IL-1beta, VCAM- 1 protein expression (P<0.01 U937+ox-LDL vs. U937, Fig. 4). The combined treatment of HIF-1alpha-siRNAs and ox-LDL reversed the effect of ox-LDL alone, decrease the protein expression of HIF-1alpha, COX2, ICAM-1, IL-1beta, VCAM-1 (P<0.01U937+HIF-1alpha-siRNAs+ox-LDL vs. U937+ox-LDL, Fig. 4)." ;
    prov:wasQuotedFrom pubmed:17343848 .
  sub:_4 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:17343848 ;
    prov:wasDerivedFrom beldoc: , sub:_3 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:33:08.907+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}