@prefix this: <http://www.tkuhn.ch/bel2nanopub/RABkVquYDNxnvkGtASmcO_MDsuYpuNZp2oSqmaNUfFS1g> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RABkVquYDNxnvkGtASmcO_MDsuYpuNZp2oSqmaNUfFS1g#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix chebi: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=> .
@prefix RNA: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: hgnc:3064;
    a RNA: .
  
  sub:_2 occursIn: obo:UBERON_0004237, species:9606;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject chebi:9516;
    a rdf:Statement .
  
  sub:assertion rdfs:label "a(CHEBI:thapsigargin) -> r(HGNC:DUSP1)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_4;
    pav:version "20131211" .
  
  sub:_3 prov:value """Table 1. Genes regulated by thapsigargin according to microarray analysis in human VSMCs  Gene ID 	Gene Name 	Cluster 	Fold Change DUSP1 (MKP-1) 	MAP kinase phosphatase 1* 	Hs.171695 	1.975 DSCR1 	Down syndrome critical region 	Hs.282326 	1.778 CYR61 	Cysteine-rich protein 61* 	Hs.8867 	1.718 FN1 	Fibronectin 1* 	Hs.203717 	1.667 GLT8D1 	Glycosyltransferase 8 domain-containing 1 	Hs.297304 	1.563 KLF6 	Kruppel-like factor 6 	Hs.285313 	1.559 PLK2 	Pol-like kinase 2* 	Hs.398157 	1.553 CXCL2 	Chemokine (C-X-C motif) ligand* 	Hs.75765 	1.538 TM4SF1 	Transmembrane 4L six family member 	Hs.351316 	1.533 GEM 	GTP-binding protein* 	Hs.345139 	1.53 FOS 	v-fos FBJ murine osteosarcoma viral oncogene homology* 	Hs.25647 	1.52 ATF3 	Activating transcription factor 3* 	Hs.460 	1.515 Genes significantly changed by ?1.5-fold when treated for 30 min with 100 nM thapsigargin compared with no treatment. In the case of multiple probe sets, exemplar is represented. VSMCs, vascular smooth muscle cells.  * Ca3+/cAMP response element (CRE)-containing consensus.""";
    prov:wasQuotedFrom pubmed:16461377 .
  
  sub:_4 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:16461377;
    prov:wasDerivedFrom beldoc:, sub:_3 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:32:55.992+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}