@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RABiQ6MeCY-IDBybgkI9-zSusKLvuJOa_5bZdo2MQvSEg> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RABiQ6MeCY-IDBybgkI9-zSusKLvuJOa_5bZdo2MQvSEg#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix sdis: <http://resource.belframework.org/belframework/1.0/namespace/selventa-legacy-diseases/> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 belv:translocationFrom go:0005622;
    belv:translocationOf sub:_2;
    belv:translocationTo go:0005576 .
  
  sub:_2 geneProductOf: hgnc:4620;
    a Protein: .
  
  sub:_3 occursIn: species:9606;
    rdf:object sub:_1;
    rdf:predicate belv:increases;
    rdf:subject sdis:tissue%20damage;
    a rdf:Statement .
  
  sub:assertion rdfs:label "path(SDIS:\"tissue damage\") -> sec(p(HGNC:GSN))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_5;
    pav:version "1.4" .
  
  sub:_4 prov:value "The gelsolin protein superfamily is a conserved family of proteins present in mammalian as well as in non-mammalian organisms. This review will focus on the role of gelsolin and gelsolin-related proteins in mammals. Gelsolin superfamily consists of seven different proteins: gelsolin, adseverin, villin, capG, advillin, supervillin and flightless I. All contain three or six homologous repeats of a domain named gelsolin-like (G) domain (fig. 1A). Gelsolin, a protein of 82-84 kDa, is the founding member of this family, exists as a cytoplasmic as well as a plasma isoform, and can bind, sever and cap actin filaments (reviewed in [2]). These isoforms are encoded by a single gene on chromosome 9 [3, 4]. The two messenger RNAs (mRNAs) encoding cytoplasmic and plasma isoforms result from alternative splicing and use alternative transcriptional initiation sites. Gelsolin is expressed in a wide variety of cell types. Its secreted form differs from the intracellular one by a 25-amino acid signaling peptide and the presence of a disulfide bond between cysteine residues at positions 188 and 201 [3, 5]. Recent studies show that the plasma gelsolin level decreases dramatically as a result of major trauma, and that reinfusion of gelsolin can protect against lung damage associated with major burn injury and other types of insults [6-8].";
    prov:wasQuotedFrom pubmed:15526166 .
  
  sub:_5 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:15526166;
    prov:wasDerivedFrom beldoc:, sub:_4 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:30:29.415+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}