http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_head http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_provenance http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://identifiers.org/ncbigene/19 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C0376358 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN4bb6fa3f2c7e069882fda4068f671e22 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/19 http://rdf.disgenet.org/resource/gda/DGN4bb6fa3f2c7e069882fda4068f671e22 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0376358 http://rdf.disgenet.org/resource/gda/DGN4bb6fa3f2c7e069882fda4068f671e22 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_provenance http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://purl.org/dc/terms/description [As expected, lycopene treatment (2.5-10 μM) significantly inhibited the proliferation of LNCaP cells during incubation for 96 h. Lycopene significantly increased the protein and mRNA expression of PPARγ and LXRα at 24 and 48 h, while the increased in the expression of ATP-binding cassette transporter 1 (ABCA1) was only evident 96 h. In addition, lycopene significantly decreased cellular total cholesterol levels and increased apoA1 protein expression at 96 h. Incubation of LNCaP cells with lycopene (10 μM) in the presence (20 μM) of a specific antagonist of PPARγ (GW9662) and LXRα (GGPP) restored the proliferation of LNCaP cells to the control levels and significantly suppressed protein expression of PPARγ and LXRα as well as increased cellular total cholesterol levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/21334870 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://purl.org/pav/importedOn 2015-02-27 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/dc/terms/created 2015-08-25T14:39:44+02:00 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v3.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP218458.RABi-b9LiHCgVfSboEdd6XwAGLbDI0og88YqyVVEX139Q http://purl.org/pav/version v3.0.0.0 http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v3.0.0