@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix hasAgent: . @prefix RNA: . @prefix species: . @prefix occursIn: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasAgent: sub:_2; a go:0042789 . sub:_2 geneProductOf: hgnc:7781; a Protein: . sub:_3 geneProductOf: hgnc:2874; a RNA: . sub:_4 occursIn: species:9606; rdf:object sub:_3; rdf:predicate belv:directlyIncreases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "tscript(p(HGNC:NFE2L1)) => r(HGNC:NQO1)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_6; pav:version "1.4" . sub:_5 prov:value "The various AREs bind to a complex of nuclear proteins from cells of different origins (15-23, 25). Analysis of ARE-nuclear protein complexes have identified several nuclear transcription factors including c-Jun, Jun-B, Jun-D, c-Fos, Fra1, Nrf1, Nrf2, YABP, ARE-BP1, MafK, Ah (aromatic hydrocarbon) receptor, and the estrogen receptor (15-32). Among these transcription factors, Nrf1 and Nrf2 have been shown to heterodimerize with c-Jun and up-regulate the ARE-mediated expression and induction of NQO1 in response to antioxidants and xenobiotics (26, 31). "; prov:wasQuotedFrom pubmed:11013233 . sub:_6 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:11013233; prov:wasDerivedFrom beldoc:, sub:_5 . } sub:pubinfo { this: dct:created "2014-07-03T14:29:52.531+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }