http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#Head http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#assertion http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#provenance http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#pubinfo http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#assertion http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:96908 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.informatics.jax.org/marker/MGI:106184 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0000893 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_3 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_2 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_1 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#assertion http://www.w3.org/2000/01/rdf-schema#label p(MGI:Mxd1) -| p(MGI:Npm1) http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_5 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_4 http://www.w3.org/ns/prov#value Overexpression of Mad1 in primary thymocytes alters the expression of predominantly genes involved in controlling cellular growth. DN thymocytes from 6- to 9-week-old Mad1+/RAG2–/– or RAG2–/– mice. In an effort to minimize experimental variation, pairwise comparisons were made using Mad1/RAG-2–/– and RAG-2–/– sample pairs that were prepared and processed in parallel. For each of three comparison sets, data from Mu11Ksub A & B arrays were combined and an expression ratio (R) was calculated for individual genes/ESTs, where R = AveDiffMadRag/AveDiffRag. Data filtering and normalization were similar to those used by Coller et al. (2000). Genes/ESTs that the AMS algorithm called ‘absent’ in both MadRag and Rag sample pairs, or where |AveDiffMadRag – AveDiffRag| ? 100, were filtered from further analysis. An exception was made for mad, where in two of three comparisons the high level of mad expression in the MadRag samples produced extensive saturation of the array probe signals, which resulted in an erroneous ‘absent’ call when the AMS gene-call algorithm was applied. Ratio values for each filtered data set were log2 transformed and normalized using mean = 0 and SD = 1. Genes/ESTs were considered significantly overexpressed in MadRag if R? 2 for each of the three pairwise comparisons. Likewise, genes/ESTs were considered underexpressed in MadRag if R? 0.5 for each of the three pairwise comparisons. http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_4 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12234922 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_5 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12234922 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#_4 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU#pubinfo http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://purl.org/dc/terms/created 2014-07-03T14:31:54.533+02:00 http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RABbgjg64l_XiASdFPrNYB7dhr0vc2CDyUpA4GwdG7PYU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234